I thought 2010 was about as bad as would get. My Mother-in-Law and Dad both died, my wife almost died from infections, and indeed, lost her big toe. I lost my weekends to my semi-invalid Father-in-Law.
2011 was worse. My wife lost another toe, my Mom died after an operation and my Father-in-Law died. I found my favorite cat Angelo dead this AM. I buried him about an hour ago.
What else going to happen 2012? I've no expectation that it's gonna get better. My guess is that my wife dies, one or both of my Pomeranians die, I lose my job, or my best friend, who's been having some health problems, dies. Or all of the above.
So bite me 2012. Here I am, ready to assume the position.