Keep in mind that bikes like the Madone and Orca are designed for racing rather than comfort. Carbon tubing for race bikes is often formed specifically for stiffness rather than vertical compliance, and the geometry is also set in a fairly aggressive position. All of which makes for a faster but less comfortable bike.
As for recommendations, I guess that depends on what issues you have with the old bike other than getting bitten by the Upgrade Bug.
At any rate, assuming you're looking for something that's carbon and a reasonable blend of speed and comfort:
Giant OCR Composite
Felt Z15, Z25
You might also consider titanium (Seven Cycles), high-end steel (Waterford, Mercian, IF), or midrange steel (Lemond Sarthe), depending on your budget.