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  1. #1
    Sumanitu taka owaci LittleBigMan's Avatar
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    False positive EPO

    Reprinted from Dr. Gabe Mirkin's website:

    Dr. Gabe Mirkin's Fitness and Health E-Zine
    July 16, 2006

    Did Lance Armstrong Cheat?

    This month, some of the favorites to win the Tour de
    France endurance bicycle race were prevented from entering
    because of suspicion that they may have taken drugs or had
    blood transfusions to raise their red blood cell counts. That
    brings up the accusation that Lance Armstrong, possibly the
    most dominant endurance bicycle racer of all time, took blood
    boosting drugs when he won the first of his seven Tour De
    France victories.
    The allegation is that Lance Armstrong’s urine, kept in
    storage for six years, had a positive test for EPO, a restricted
    drug that raises blood levels of oxygen-carrying and
    performance-enhancing hemoglobin. An article published in this
    month’s issue of the prestigious medical journal, Blood (June 15,
    2006) shows that after competing in any athletic event, any
    athlete could have a false positive urine test for EPO.
    The test for EPO is done by injecting the protein, EPO,
    into animals so that their bodies produce special proteins called
    antibodies that attach to EPO. The antibodies are put on a
    special plate, and the test urine is added. If the urine contains
    EPO, a band consisting of the antibody tied to the EPO appears
    on the special plate.
    Researchers at Catholic University of Leuven in Belgium
    showed that “this widely used test can occasionally lead to the
    false-positive detection of EPO in postexercise, protein-rich
    urine.” Any athlete can have a false positive test with this
    procedure. Most people with healthy kidneys do not spill protein
    in their urine, but after strenuous exercise, athletes with normal
    kidneys often spill protein into their urine. For example, more
    than 80 percent of runners spilled protein into their urines after
    running the Boston Marathon. The authors state that the
    antibodies that are used in the test can attach to any protein in
    the urine, not just EPO.
    No worries

  2. #2
    me have long head tube TallRider's Avatar
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    Wow. Roberto Heras must be licking his chops. And honestly, if he did take EPO, it would have made near-zero sense for him to take it in the last few days of the Vuelta. He had a big lead on Menchov, and didn't need to win the ITT, so the possible payoff diminishes greatly compared to the risk of getting caught.

  3. #3
    semifreddo amartuerer 'nother's Avatar
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    There are other factors that could suggest a "false positive" as well; apparently hematocrit levels will increase when dehydrated.

    But the fact remains, it's extremely difficult to prove that anyone did or did not take it. The accused will rely on the absence of "reliable proof", and the accusers will rely on circumstantial evidence and insinuation. I don't see any magic bullet for the goal of getting cycling free of doping.
    Can you pass the test?
    Yield to Life.

  4. #4
    HJR
    HJR is offline
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    I am not a hundred percent positive about this but are not the samples taken before stages, not after.
    Cervelo Soloist Team
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  5. #5
    me have long head tube TallRider's Avatar
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    Quote Originally Posted by HJR
    I am not a hundred percent positive about this but are not the samples taken before stages, not after.
    Oh yeah, I'm pretty sure you're right. Sorry, Heras.

  6. #6
    a blend of wit and charm Moochers_Dad's Avatar
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    Quote Originally Posted by HJR
    I am not a hundred percent positive about this but are not the samples taken before stages, not after.
    There are some taken before at random and then after each stage the stage winner is tested and some other riders at random. I have read that blood doping is so effective, you can get tested before a stage, come up clean and inject your own red blood cells back into you 20 minutes before the stage begins.

    Also, since it's possible for someone to use a catheter and fill his own kidneys with clean, synthetic urine; urine testing is done after each stage. Blood testing is done at random througout the race, day and night at.

    According to his website, last year on the eve of a rest day, Fabian Wegmann and a teammate had stayed up late watching television, only to be woken up at 6am by the "vampires" coming for their blood.

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