Now, this is totally disregarding cost, and is probably not all that practical. Just what I imagine would be badass, with some stuff that may not exist. I wouldn't want to run my nice custom bike as a commuter.
*Columbus Zona Steel w/ carbon fork
*Fully housed cables w/ internal routing
*Similar geometry to my Crux, just optimized for myself
*1x10 SRAM Rival/Force groupset (brifters would be v-brake compatible haha)
*BB30 Bottom Bracket
*Paul Motolite Brakes
*3 Zipp 303 Tubular Wheelsets w/ Michelin Mud for wet stuff, Challengo Grifo XS for dry stuff, and Specialized Tracer for the pit wheels (these are pretty good all-around tires, imho)