Yes, Selle Anatomica will cut out the center of your Brooks. But, you should be aware that Selle Anatomica Titanico saddles are laminated. That is, they have an added layer of leather on the under side that strengthens the web and probably helps support the saddle when you cut out a large section of it. Titanico saddles are very fine products, as are Brooks. They will do a good job on the cutout. You might try writing to a gentlman I met a couple years ago at Seattle Bike Expo who had this done. I saw the saddle and it looked fine. I think his name is Tom and he manufactures a nifty ttype of touring kick-stand. His site is clickstand.com
EDIT: IMO, almost all pressure related problems on a leather saddle will be solved by small adjustments as you and the saddle get to know each other.