I'm out in O'Fallon, MO. Drivers in STL just can't drive worth s**t, and they're aggressive and fast, too. The combination makes for some interesting road riding.
I generally ride loops out of my driveway, carefully picking my way over to Winghaven, up towards Lake STL and back. I have a couple of different 10 mile loops that are next to each other so I mix and match pieces of them to try to get 12-15 miles a day in.