Originally Posted by fordfasterr
Then what is the point of taking amino's ??? LOL
Aminos are the basic building blocks of muscle. Aminos can also trigger anabolism, the cornerstone of muscle growth. While there are nearly two dozen different amino acids, only a select few are absolutely essential for igniting the anabolic drive, as new research has shown. Not surprisingly, these required aminos are the same ones found in human muscle protein.
Once safely past the liver, uncoupled aminos enter systemic circulation, where they can exert their pharmacological actions-vasodilatation and anabolism. When combined with training, they can actually help your body deliver more nutrients to your working muscles, recover more quickly, and build new muscle mass by enhancing protein synthesis, improving net muscle protein balance, and preventing muscle breakdown.
Over the years, words like "protein" and "amino acids" have been thrown together so much, they usually mean the same thing to a lot of people. An effective amino supplement can do things whole proteins can't. Now whole or intact protein from food and powders like whey, casein, egg or soy are made up of amino acids linked together by chemical bonds. In the small intestines, special enzymes get to breaking down the dietary proteins in smaller peptides and individual aminos. Whole proteins must first be broken down into these smaller peptides and individual aminos before they can be absorbed. Some measurements indicate that 70-80% of 15g of milk protein in a meal get absorbed in 3 hours.
While it takes a lot longer for it to get digested, dietary protein is important because it gives your body the basics building blocks it needs-a wide range of amino acids that can be used to restore amino acid levels in the body to help new tissue growth and regulate important bodily functions. For accomplishing these very basic functions, supplement wise, you can't beat protein powders. But think of protein in foods and shakes as gold ore. There's pure gold in the rock, but you've gotta get it out to be able to use it. You can definitely get it out, but it takes more time and work.
Individual amino acids can produce pharmacological and physiological effects such as anabolism, hormone regulation (growth hormone, insulin), immunomodulation, neurotransmitter function, and the like. Amino acids, in other words, have the ability to be more than just building blocks for the body. Unlike protein powders, aminos can exert certain anabolic and anti-catabolic effects and impact hormonal functions.
In the real world, what this means is that the right ratios, forms, and kinds of individual aminos can increase strength, shorten recovery times, reduce fatigue, and increase lean mass.
There are studies that argue that increasing protein intakes too much can actually hurt, not help. This is the Protein Paradox. By eating more protein-rich foods and protein shakes, scientists believe this can actually reduce the availability of aminos in tissues due to wastage (catabolism). This reduction of aminos can then put the brakes on protein synthesis. For example, drinking a lot of whey protein shakes may give you a lot of BCAAs, but with high protein diets, these BCAAs can be quickly catabolized. Over the long run, researchers speculate that high protein diets can lead to metabolic imbalances, deficiencies of key amino acids in the body, and suppress protein synthesis.
Uncoupled aminos are different in a more fundamental way. They can actually bypass the liver (where aminos are usually deaminated and ultimately converted to urea) and enter systemic circulation. When this happens, the pharmacological benefits can be realized. Here's how it works. When you eat a steak or drink a protein shake, the aminos get caught up and processed in the liver. Uncoupled amino acids, on the other hand, have the ability actually bypass the liver. Once ingested, uncoupled aminos can form a "bolus"-think of this as a therapeutic mass of aminos.
Due to this protective bolus, when the uncoupled aminos reach the liver, they can escape the liver's processing. In other words, these aminos can enter into systemic circulation quickly and reach their target areas to exert the pharmacological and physiological effects.
Additionally, only with free "uncoupled" aminos can you precisely complex and formulate the right kinds of aminos, in the right ratios. It's not just a matter of throwing uncoupled aminos in there. You have to also choose the right aminos and in the right amounts relative to the other aminos.
There are two accepted categories of amino acids: essential (indispensable) and non-essential (dispensable). Essential amino acids (EAA) are those that are, well, essential. The body can't make them on their own; it must obtain them from the foods and supplements you eat. Non-essential amino acids (NEAA), on the other hand, can be synthesized by the body.
The human body can maintain nitrogen balance on just the essential amino acids if necessary. Non-essential amino acids aren't necessary to stimulate net protein synthesis and anabolism. In concrete terms, researchers at the University of Texas found that a 6g dose of essential amino acids was about twice as effective as a 6g serving of mixed amino acids in stimulating protein synthesis.
All in all, amino acids are pretty simple things, but supplementation can be complex. It's not just a matter of popping a few amino tablets or drinking a protein shake. With the body in an anabolic state, the body can recover more quickly and efficiently for gains. By taking BCAA's pre- and post-training, the anabolic switch is turned on and remains on during the most critical nutritional window of opportunity.