Reading a post by carbonfiber boy lead my to post this abstract I found that contrasts some of what was posted in the insulin thread.
Apparently according to this abstract weight loss on a high protein diet or high CHO diet is bennificial. It claims that biomarkers of CVD and other diseases are reduced using either method of weight loss.
Long-term effects of a high-protein weight-loss diet1,2,3
Peter M Clifton, Jennifer B Keogh and Manny Noakes
1 From CSIRO Human Nutrition, Adelaide, Australia
Background: Evidence that high-protein diets are an effective strategy for the maintenance of long-term weight loss is limited.
Objective: The objective was to determine the efficacy of a higher protein intake on the maintenance of weight loss after 64 wk of follow-up.
Design: Seventy-nine healthy women with a mean (±SD) age of 49 ± 9 y and a body mass index (in kg/m2) of 32.8 ± 3.5 completed an intensive 12-wk weight-loss program and 52 wk of follow-up to compare the effects on weight-loss maintenance of a high-protein (HP) diet (34% of energy) or a high-carbohydrate (HC) diet (64% of energy).
Results: Mean (±SD) weight loss was not significantly different between groups: (HP: 4.6 ± 5.5 kg; HC: 4.4 ± 6.1 kg). Protein intake (g) from dietary records at 64 wk was directly related to weight loss (P < 0.0001), accounting for 15% of the variance. Protein intake as a percentage of energy was also related to weight change (P = 0.003), accounting for 10% of the variance. In the upper tertile (88 g protein/d), weight loss was 6.5 ± 7.5 and 3.4 ± 4.4 kg (P = 0.03) in the 2 lower tertiles, respectively. This difference did not translate to a difference in central fat loss between groups. Lipids, glucose, insulin, C-reactive protein, and homocysteine all improved with weight loss and were not significantly different between groups. HDL cholesterol rose by 20%. Higher serum vitamin B-12 was observed in the HP group, and folate concentrations were not significantly different between groups.
Conclusions: A reported higher protein intake appears to confer some weight-loss benefit. Cardiovascular disease risk factors, biomarkers of disease, and serum vitamins and minerals improved with no differences between groups.
Key Words: Weight loss • high-protein diet • abdominal fat • body composition
Here is another one that looked at short term weight loss with ad libitum high protein low carb, and high protein moderate carb intake.
Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum 1,2,3
Alexandra M Johnstone, Graham W Horgan, Sandra D Murison, David M Bremner and Gerald E Lobley
1 From the Division of Obesity and Metabolic Health (AMJ, SDM, DMB, and GEL) and Biomathematics and Statistics Scotland (GWH), Rowett Research Institute, Aberdeen, United Kingdom
Background: Altering the macronutrient composition of the diet influences hunger and satiety. Studies have compared high- and low-protein diets, but there are few data on carbohydrate content and ketosis on motivation to eat and ad libitum intake.
Objective: We aimed to compare the hunger, appetite, and weight-loss responses to a high-protein, low-carbohydrate [(LC) ketogenic] and those to a high-protein, medium-carbohydrate [(MC) nonketogenic] diet in obese men feeding ad libitum.
Design: Seventeen obese men were studied in a residential trial; food was provided daily. Subjects were offered 2 high-protein (30% of energy) ad libitum diets, each for a 4-wk period—an LC (4% carbohydrate) ketogenic diet and an MC (35% carbohydrate) diet—randomized in a crossover design. Body weight was measured daily, and ketosis was monitored by analysis of plasma and urine samples. Hunger was assessed by using a computerized visual analogue system.
Results: Ad libitum energy intakes were lower with the LC diet than with the MC diet [P = 0.02; SE of the difference (SED): 0.27] at 7.25 and 7.95 MJ/d, respectively. Over the 4-wk period, hunger was significantly lower (P = 0.014; SED: 1.76) and weight loss was significantly greater (P = 0.006; SED: 0.62) with the LC diet (6.34 kg) than with the MC diet (4.35 kg). The LC diet induced ketosis with mean 3-hydroxybutyrate concentrations of 1.52 mmol/L in plasma (P = 0.036 from baseline; SED: 0.62) and 2.99 mmol/L in urine (P < 0.001 from baseline; SED: 0.36).
Conclusion: In the short term, high-protein, low-carbohydrate ketogenic diets reduce hunger and lower food intake significantly more than do high-protein, medium-carbohydrate nonketogenic diets.
Key Words: Ketogenic low-carbohydrate diets • weight loss • high-protein diets • body composition
And here is the news report
Monday, January 21, 2008
By Joene Hendry
NEW YORK (Reuters Health) - A study in obese men suggests that a high-protein, low-carbohydrate diet is most effective for curbing hunger and promoting weight loss.
High-protein intake promotes satiety and, when combined with very low carbohydrate intake, causes the body to use fat reserves, often resulting in short-term weight loss, the researchers note in the American Journal of Clinical Nutrition.
"Hunger is one of the main reasons diets fail, thus understanding more about appetite control during dieting will allow us to design diets that achieve weight loss, without feeling hunger," Dr. Alexandra M. Johnstone told Reuters Health.
Johnstone, of the Rowett Research Institute in Aberdeen, United Kingdom, and colleagues compared hunger, appetite, and weight loss measures in 17 obese men. The men, aged 38 years on average, lived in a nutrition laboratory setting while they participated in two short-term diet interventions.
The men could freely chose the amount of food they ate from carefully prepared daily meals containing 30 percent of energy from protein and either low-carbohydrate content (4 percent) or medium-carbohydrate content (35 percent), plus respective fat contents of 66 percent and 35 percent.
During the first 4-week period, the men were randomly assigned to the high-protein, low-carbohydrate meals or the high-protein, moderate-carbohydrate meals. They then followed a month-long fixed, mandatory maintenance diet before crossing over to the opposite carbohydrate-level diet for a second 4-week period.
While weight-loss occurred with both diets, the high-protein, low-carbohydrate diet resulted in greater weight loss and less hunger.
The investigators are using these findings to help them further assess the brain's link with hunger in follow-up studies utilizing brain imaging.
The current results, Johnstone and colleagues say, confirm that high-protein, low-carbohydrate diets result in satiety and weight loss, but they suggest that high-protein diets only be followed for short periods and under medical supervision as they are not suitable for everyone.
SOURCE: American Journal of Clinical Nutrition, January 2008