I concur with the prevailing sentiment -- with half-step up front and the rear wheel pushed all the way back, you should be able to make it work, but you'll have to pay attention to chain length. 49-45 / 13-28 should make a nice half-step. The other way to play it is 1.5-step, e.g. 52-42 / 15-17-19-22-25, which the derailleur can handle with aplomb.
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"Far and away the best prize that life offers is the chance to work hard at work worth doing." --Theodore Roosevelt
Capo: 1959 Modell Campagnolo, S/N 40324; 1960 Sieger (2), S/N 42624, 42597
Carlton: 1962 Franco Suisse, S/N K7911
Peugeot: 1970 UO-8, S/N 0010468
Bianchi: 1982 Campione d'Italia, S/N 1.M9914
Schwinn: 1988 Project KOM-10, S/N F804069