Yes. I've had them on my road bike since 2003 and average a flat every 1500-2000 miles. I also had them (different brand) on my commuter bike (when I was a bike commuter) and averaged a flat every 1500 miles.
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The Lord is merciful and gracious, slow to anger and abounding in steadfast love. - Psalm 103:8
I am a cyclist. I am not the fastest or the fittest. But I will get to where I'm going with a smile on my face.