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Old 03-17-10, 07:06 PM
  #8  
tadawdy
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We should not be attempting to "control inflammation" without first attempting to remove the item(s) that are causing the inflammation.
You're right, in that acute inflammation can be useful. It is a protective and healing mechanism.

Chronic, low-level inflammation is not, though. The article also says that the most exciting thing is that it may help us understand the precise mechanism of inflammation better, not that the drug itself proved useful (though that is good in itself). Don't forget that until relatively recently, the immune and inflammatory aspects of atherosclerosis were not widely recognized. It was largely considered a passive process, which hurt our efforts to treat it. Even our understanding of cholesterol and other (possibly better) predictors of heart disease, something we have held as truth for some time, is evolving at this moment. Some of these discoveries were made by observations of the effects of some drugs, such as aspirin.

If you live long enough, no matter what you eat or do, some aging process will catch you, and many of these are inflammation-mediated. Some people are also naturally prone to these things. People of "healthy" build have heart attacks, too. So do people with "normal" cholesterol levels. People who ride their bikes a lot also have heart attacks. Getting old sure does suck. It's all downhill from about 20.

Why not have the drugs handy when other measures fail?

We can figure out some of the root causes of how obesity promotes inflammation
Is that real???... Did I just read that.
I don't see why you're so surprised, unless you claim to know something no one else does. Why is being fat bad for us, exactly? How does it cause inflammation? "Well, clearly it's unnatural and fat people eat McDonald's, so fat causes inflammation" isn't good enough. What is the specific physiology there? The answer is that we don't really know. It may be possible that obesity and other poor health habits are simply correlative, and that obesity isn't actually what we should be worried about.

Saying that everything can be fixed by eating a proper (read: upper-class, educated, white people food) diet, or the Paleo diet, or the Mediterranean diet, or whatever fad is hot this month is dilettantism at best.
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