Unless it's a mixte frame, which are really quite stiff and can be nearly the equivalent of a double-triangle in the same material.

I'd generally stay away from Alex wheels- my wife's A320's came apart after only about 1500 miles. I'd go with something like Mavic Open-Pro rims on Ultegra hubs with double-butted spokes. The wheelset can cost $250, but it's worth it; you'd end up buying a better wheelset anyway later. I got mine from Performance bike for $199, but that was a while ago. If you do go with a factory-built wheelset, make sure one of your fanatic friends evens the tension on the spokes and does a stress relief and truing on it.

Also, if your frame is older, you may need to cold-set the rear dropouts to 130 mm from the existing 126 mm. It's not hard, but it makes the back wheel go in better.

Also, if you plan on touring, maybe get a triple trekking crankset for lower gears. A road double is way too high gearing for any kind of touring unless you have knees of steel. The Sugino XD500 is really good, but you can make the XD300 work plenty well if you don't mind steel chainrings. Either will be cheaper than the 105, too.

The Classic and Vintage forum has a thread about retro roadies with good equipment ideas.

+1 on the pics.