Thanks FBinNY! I just had this happen (exactly as the OP described, large hole right outside reinforced area, corresponding 'pimple' on the opposite side, fantastic cloth rim strips that seem perfect) and was racking my brain trying to figure out what could possibly have caused it (there was no 'pop', it was just flat when I checked it this morning after riding last night). Your description was very informative and helpful! Also, thanks for the advice for preventing this in the future!