I have Ergon GC-2 grips & they made a huge change in both comfort & climbing.
I've run ODI lock-ons for 10+yrs & had been having some soreness, numbness issues after being out 30+ miles. After I slapped those on, long rides are no longer an issue (on my hands). I can move my hand position around a bit, probly 4 different places during a ride.
Climbing was improved (riding SS) as I could move my hands around a bit to gain more traction.
Wanna give the GP-1s a shot on my HT next.