I run tubeless on my all mountain bike.. Nicer ride, run a lower pressure, no flats..
I run Stan's in the tubeless and I've not had a flat on my tubeless tires.. I live in Tucson, so no flats is amazing.. The Stan's helps though, I've run over cactus in the middle of the trail and hear the Stan's seal it up. To be fair, I use Stan's in my hardtail too and haven't had a flat in ages, including running with tubes.
On the road, I use tubes and Forte Strada K tires, I can't remember the last time I've had a flat, maybe once in 1500 miles..