If you are going to spend all that money, why not just get a new bike, you will get a bike with warranty, and no compatibility issues, Bikesdirect will pointed out as a good place to get good value full builds.
Thinking with your seize / weight, you should be looking at a 29er, with front suspension, a CX bike has drop bars, which will be harder to use if you do ever go off road, and get some semi slick tires for it.
A LBS should be able to do a parts build, but would probably put a big premium on it.