Hello Jim!

Living in Greece from the mid 80's, all I can say is that you should definitely take into account what thesearethesuns is saying. Road conditions vary from newly constructed to pot-hole stricken death-traps. But what you have to really take into account is the mentality of the typical Greek drivers, especially when on country roads, which don't know how to react to cyclists sharing the same space. I've had cars brush past me doing more than 70 miles an hour, and in other situations had an elderly driver tailgate me because he was afraid to overtake me! Trucks and buses are especially dangerous since the drivers are usually over-worked and tired.

The upside is that this is a very beautiful country, and you are guaranteed to be mesmerized by it! The first route you talked is especially beautiful but has some major climbs when reaching Kalabaka.
One more thing I need to mention... Greece has serious problems with stray animals, and you will find packs of dogs on country lanes, so keep an eye out for them.

Feel free to contact me if you need any further info!

Telly