I ride a women's CAAD10 (48-inch frame). Went with the WSD mainly because of the narrower handlebars (I'm 5'2" and pretty small of bone), and because they had that frame in stock, I sat on this bike and liked how it felt, but next time around I wouldn't shy away from getting a men's bike that fit, and perhaps just swapping out the handlebars. Several of my teammates ride unisex/men's bikes and have no complaints.