I have ridden Selle Italia Flites (the original) since the mid-90's. I currently have them on my two road bikes. During this time I tried a Brooks Swift for a year or two, then sold it. It just wasn't as comfy as the Flite.
I just recently picked up a Selle SMP Glider, which is the first cutout saddle I've ever tried. I put it on my touring bike with a slight nose-down tilt as per instructions, then rode it 50 miles in absolute comfort with no further adjustment.