Originally Posted by
well biked
We check the limit screw adjustments any time we install a different rear wheel or install a cassette at our shop. Different parts don't always line up the same, as evidenced by the photo in post #1.
+1 Even two "identical" cassettes by the same maker and with the same gear range may not line up with the rear derailleur exactly the same way. There are manufacturing tolerances with everything and you can't assume the limit screws set correctly for your current cassette will be good for its replacement. You have to check the adjustments for every change.