As long as you wear shorts and wash them after every ride (which you should do no matter the saddle), you should be golden. But still, don't eat the yellow snow.
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Bikes: 1996 Eddy Merckx Titanium EX, 1989/90 Colnago Super(issimo?) Piu(?), 1990 Concorde Aquila(hit by car while riding), others in build queue "when I get the time"