On roads where heavy vehicle traffic is moving at speeds in excess of 25-mph and especially if speeds are 45+ mph I would much prefer a road that has a beautiful wide shoulder edge like this to ride on in the "Out" position:
For in town traffic where speed limits do not exceed 25mph I find it much easier and safer to always ride "IN" or as I call it "ALL IN" and take a center lane position and ride as if I were a motorcycle: