With a name like that, I think a Cannondale BadBoy would be right up your alley...
My wife has one and loves it! Disc brakes, comfortable, sloping geometry so she can get on/off of it easily, and hers has the front suspension headshok fork. It comes with 700c wheels, and plenty of room for larger, cushier tires. If she sever wanted to, she could run 26" mtb wheels on it.