Wow...what bunch of nonsense.
I think the lingua franca that is the word
road bike has a fairly obvious meaning.
You're all arguing with Doge for the sake of it.
...and I say that as an "All-Road" rider.
To answer the OP's question...too soon to tell. ENVE's move is pretty bold, nevertheless those are probably some high performance aero wheels in the real world, and depending on the tire, it's going to be all about lower psi, yet good speed because sidewalls will be straighter, road buzz even more effectively nullified, and contact patch is shorter...
It's cool that they did this, they probably saved the weight (older version of 4.5 is quite heavier) due to not having the hindrance of a brake track...and although disc brakes weigh marginally more, it isn't rotating mass at the edge of the wheel...