Originally Posted by
Dan Burkhart
If you have chainstay clearance,( quite likely not) you may try mounting the 53 tooth on the inside of the spider. That should put the chainline slightly inboard of the center of the cassette and would improve the situation.
It will never be ideal, but it should be functional.
Thought about that, but it looks like that might lead to a similar issue on the shorter gears, which I'm in more often.