I ride a Litespeed Classic (3Al/2.5V Ti), but I can't say it's a better ride than a good steel frame. I like it for the lightness and freedom from corrosion worries. If I ever feel the need to upgrade, I plan to check out a good, light, steel (specifically, Serotta) frame.
I've had the Classic for a little over 2 years, and in that time, I really haven't spent much time thinking about a new bike. Maybe a new gruppo, or wheels, but not the frame. And I did e-bay another decent bike I had, because I just never rode it. I guess that says something.