I'm a wool layers + windstopper kinda person. I have different wools (light and medium merino baselayers, and some old Banana Republic merino sweaters) that get used separately and in different combinations depending on factors like temperature, humidity, and my mood.
It goes something like this:
Stage 1: Wool + jersey
Stage 2: Wool + jersey + light (vented) wind jacket
Stage 3: Wool + jersey + (vented) softshell (with Gore windstopper)
Stage 4: Wool + More Wool + softshell. (At this point I've generally given up on using a jersey for its storage pockets.)
More wool gets added depending on how cold it gets; things other than a jersey go over the base layer if I'm going to work rather than just riding around.
I have some poly layers as well, and they aren't bad, but they get rancid quickly. All my fleeces are like 20 years old and way thick/baggy...what I have works, so I haven't bothered to shell out for a modern fleece.