I have a 2x11 bike and I don't use the top 2 cogs with the big chainring, nor the bottom 2 cogs with the small one.
Unless I need a drastic change of cadence or my speed changed suddenly (usual on a mountain bike, but not on a road bike), when moving from big chainring to small I usually upshift a couple or even 3 cogs to compensate. I do the opposite when shifting to the big ring.