dddd

There is no "perfect" chainline anyway, because it depends on how the rider sequences their front and rear shifts, and on how much time they spend in which particular combination of sprockets.

I tend toward a shortest-possible chainline because I prefer not to have to shift down to the small chainring frequently, so ideally my large chainring is more centered with the freewheel than the small chainring. I do find a lot of variation though on bikes that I take in, and tend to shorten the spindle eventually (or perhaps change to a symmetrical spindle of the same length).
It's just me though, I find it near-impossible to get used to a double crank setup with a long chainline dimension.