I've had small differences with my Favero Assioma Duo's & my Kickr18. The difference is up to ~3-4%, but seems to lessen on longer Zwift rides.
Last winter, I did a static weight test, made some adjustments, did several spin-downs & pedal calibrations & got average power within one watt.
This year it's back to ~3% after the pedals were on another bike for the season.
I'll go through the same process of adjustments soon to get everything to agree.
I also have a Favero Assioma Uno, and the difference with that varied greatly, so I don't use it anymore.
A difference of a few watts is normal (+/- accuracy, drivetrain loss) but 25% is too far off.