Putting San Marino and Ventura at the start and end points into Strava's route creator, I get a route through Glendale - Van Nuys - Santa Susana Pass - Simi Valley - Camarillo - Ventura. 88 miles, 2200' climbing. You won't get the nice ocean views, but you also don't get the PCH traffic challenges.
__________________
"Swedish fish. They're protein shaped." - livedarklions