Old 10-11-06, 05:39 AM
  #2  
HillRider
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Location: Pittsburgh, PA
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Bikes: '96 Litespeed Catalyst, '05 Litespeed Firenze, '06 Litespeed Tuscany, '20 Surly Midnight Special, All are 3x10. It is hilly around here!

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Tightened properly and using a proper design (Campy or Shimano-type internal cam with steel rods) qr skewers will exert at least as much clamping force as axle nuts and can't loosen by themselves so a standard front facing horizontal dropout should be fine with the qr hub.

However, you must avoid the boutique skewers with the external cam design and Ti rods.
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