I started taking Omega 3 last Nov. and just had my cholesterol checked about one month ago. It was down 13 pts from last year without any huge change it diet. I've since been trying to eat much better also. Family has a history of high cholesterol and heart disease. I'll be 45 this summer with two young daughters so figure it's time to take better care. BP is also borderline hypertensive so I started biking last summer mainly for fitness issues but sure do love to just ride.
I also take a multi vitamin once/day and glucosamine twice. Figure it can't really hurt my joints so it's more of a preventative measure.
Also, I do supplement with a whey protein shake after a strenuous training ride or weight lifting.