Based on my experience, any road safe enough for a DF is also safe enough for a bent. Like others, based on driver responses, it seems a trike may be a bit safer than anything on two wheels.
In daylight, for most drivers, most of the time, a squirrel is plenty visible. In that same daylight, for some drivers, some of the time, a huge emergency vehicle with blindingly bright lights and loud siren is quite invisible.
On my low tadpole, the main issue is my height limited sight lines. I simply assume that what I cannot see might hurt me and use appropriate caution.
I am certainly a safer rider on a trike than on a DF or two-wheeled bent because I am more willing to greatly reduce speed as may be appropriate.