Max

https://www.cnn.com/2003/HEALTH/diet.....ap/index.html

I always doubted that sitting 8 hours in the office and driving for 1 hour every day can be compensated by 40 minutes of gym activity couple of times per week.

Guest

https://www.usatoday.com/usatonline/2...6/5244888s.htm

This is the article I read I read in the USA Today. People were complaining because researchers bumped up the recommended exercise to an hour a day- they seemed like they were giving up because they couldn't do all that exercise in one day.

Never mind the fact that about half the errands these people do run can knock out about 30 minutes of exercise alone- and the other 30 minutes could be knocked out by doing stuff like taking the stairs instead of the elevator, walking to the train or bus instead of getting a ride, walking to people's offices to talk to them rather than buzzing them on the intercom, etc. That's 5 days knocked out right there, then on the weekends, they can do longer workouts, like a run or some cycling or rollerblading- whatever!

I think someone just needs to educate them on how they can incorporate activities into their daily work and errands so that they can start living healthier, that's all.

Koffee

DnvrFox

We used to have some neighbors who would get together on Saturdays to watch NFL football. Instead of walking to the neighbor's house 3 houses away, they would get in the car and drive! This was in good weather.

Guest

What's wrong with that?

If he's trying to keep his new shoes from being scuffed, it's a worthy reason to drive. Sheesh!



Some people are just incredibly lazy. My brother will drive to the end of the block to hook up with friends, then complain about the big stomach he's acquired over the past 2 years and call me for exercises to do to get rid of the stomach. Go figure.

jatkins679

Well, with all due respect and no offense intended, I don't think that's exactly what these sorts of studies are talking about. When those studies suggest 20, 30, 60 or however minutes of exercise a day, they are almost always suggesting sustained exercise that gets and keeps the heart rate in a moderately-strenuous level. Walking up a flight of stairs three times a day but not back-to-back isn't that.

Every little bit of exercise counts, mind you. But again, that's not what these sorts of studies are addressing.

I think what missing in these sorts of discussions in the press is that it simply shouldn't be that difficult for people to pencil out 20 or 30 minutes a day to walk briskly around the neighborhood and that for most people, 'not having enough time' is simply a cop-out.

Most people's lives are pretty harried, that's very true. But when you step back for a second, I think you have to look at all the excuses people have and all the things people often do in lieu of exercising. TV is the biggest thing. One measly sit-com a night you'd miss if you got out and walked, that's 30 minutes. Hell, that's not even 30 minutes of sit-com because of commercials!

(It would also contribute to lessening one of the most common concerns people have nowadays: crime. Real or not, people see crime as a problem. Yet people out and about is a clear deterent to criminals and you are much, much more likely to be attacked while at home than anywhere else anyway. So why not get out and do something that has a real affect on a problem you most likely find significant in your life: walk around your neighborhood.)

Driving is the other thing. Most errands run in automobiles are one stop. So once a week you can't get out of your car and hop on a bike to pick up your photos? Or to walk to the store for that loaf of bread with (gasp!!) your kids and have some quality time with them at the same time?

Yeah, yeah: walking or cycling to the store can be dangerous because (gasp!!) there are cars out there and one might run me over. Uh huh. So instead people will contribute to the problem and write their own excuse and drive. Very interesting......

Guest

I feel what you're saying.

However, I think that the majority of people do not do any kind of physical activity. If they do any exercise, it's so little, it doesn't have any real benefit to them.

When I go overseas, I see people doing everyday activities, and most countries do not have the obesity problems we have. In addition, I don't think the majority of people in other countries spend more time at the gym to stay in shape. People in other countries are just overall generally more physically active than in our country, and they end up healthier than us.

It is unfortunate that we have to be forced to take an hour out of our day to do higher intensity exercise to get the same benefit as Suzette Q in another country who simply incorporates phsical activity into their daily living- walking to the store, work, the train, etc., walking to the market, taking the stairs, etc. If people would just take more time (and less time wasted on things like television and watching sporting events, etc.) to do the things they would normally skip doing and incorporate more active lifestyles into their routines, I don't think we'd have half the problems we have right now. Of course, nutrition also plays a big part in this too.

One winter during my college, I decided to not take the bus from one class to the next, take the stairs instead of elevators, and walk to the store and back instead of taking the bus. With all the classes I was taking, at the end of the winter, I'd dropped almost 20 pounds! I couldn't believe how easy it was.

I'm sure if people tried hard enough, they could find plenty of ways to get the exercise in- it's not just the stair walking, it's everything- they just need to evaluate what they do now and see what they can change. Healthy lifestyles require conscious changes in their habits, and I don't think a lot of people are willing or ready to do this, unfortunately.

Pete Clark

Most sedentary folks can't do an hour of intense exercise. They have to work up to it by starting with 20 or 30 minute walks. The guidelines are intended to speak to sedentary people, not those of us who already know we can't do without an hour's workout.

jatkins679

No, apparently almost half of all American adults (if I remember the statistic correctly) do not get any regular exercise at all. At first, that stat astounded me. But upon further reflection, it really doesn't.

I think there are a couple of things going on when we look at Americans versus others around the world. One is that we are a car-culture and have built our societies around the automobile. That (obviously) doesn't lend itself to getting and/or staying physically fit. Even our cherished memories often revolve around the car: car hops, drive-in movies, road trips, etc.

It's gotten to the point that we shy away from even walking or biking in our own neighborhoods because of cars. There is something so viscerally wrong with that.

The other thing is the amount of food we Americans eat. When I lived in Alaska, I'd run into foreign tourists all the time. And they all said the same thing: Americans eat a lot, we eat all the time, and when we eat food portions are huge. Even those from commonwealth countries, with whom we generally have more in common with than any other countries, would say very often say that.

More than anything else, I think eating is our societal problem with fitness. Clearly, calories alone would suggest that intake and not output is where we are going wrong: most people would be challenged to burn 300 calories in any given workout, yet that is about the number of calories in one McD's hamburger.... but of course many/most of us think nothing of eating a Super Sized Quarter Pounder with cheese, fries, and a coke which has a whopping 1550 calories. That's not a whole lot less than the necessary intake a typical adult needs a day (about 2,000).

Pretty obscene, huh?

ChipRGW

You forgot the apple pie...

Max

I do not think that Americans eat more than others. I think the problem is in the car usage.

In the USA is is about the 3rd generation, which lives in the era of complete automobilization, i.e. when every family can afford the car.

In Europe it is the 2nd, in the FSU - the 1st generation.

I saw in America, what does not exist anywhere else. For example, one can use ATM without leaving the car, or buy goods in the apotheke from inside the car, or food in a restaurant. There are special windows in the business buildings, on the back side, to which a car can drive in for the driver to be served, while sitting in the car.

The problem is that the driving in the car like this is considered to be "cool", but walking is considered to be "not cool". However in reality all this is vice versa. Driving like these leads to obesity and environment degradation, what is not cool at all, but walking and cycling lead to fitness and environment sustainability, what is really cool.

There is America and America. In Washington D.C. there are a lot of cyclists. In the area of Pentagon I saw a lot of fit people jogging at any time of the day.

But in small towns there are streets, which does not even have sidewalks. Still there are houses on these streets. I remember as we decided to walk to the shop in Williamsport, Maryland. We walked on the side of the road about 1.5 km, since there was no sidewalk. And people were visibly confused seeing us walking along the road.

I am afraid this internal belief that driving is "cool" is spreading around the globe. It is transmitted by incessant ads on TV, magazines, radio, newspapers, etc. I think the next generation in my country will be also about the same obese, since it is worsening incrementally.

It seems that the problem is in these ads, because driving is not easier than cycling. For me to go to the parking lot, clean the windshield, warm the engine, crawl in the hot dusty car is much more tiring than hop on my bike and take off to the office in no time. Let alone to drive to the service center on the day off, or, god forbid, to the road police for car technical inspection - brrrhhh...

It is like a stereotype. Remember those stupid stereotypes, that a true man must smoke, that a good woman should stay at home with kids by all means, etc.

caloso

Max: Insightful post. As an American, I appreciate your perspective on this, and it confirms my own observations. I lived for year in Almaty, Kazakhstan. Although remote, Almaty is at or above the standards of the big CIS cities and people lived well. Not everyone had a car, though, and certainly they didn't have a car for every member of the family.

I walked a great deal, hiked in the mountains above town, and even though I ate a much fattier diet than here, my weight stayed down. Lot to be said for not having a car.

Pete Clark

I have observed that many people find it increasingly difficult to walk more than a few feet. Without a car, they wouldn't be able to get around at all.

If we don't exercise, we lose more and more muscle mass every year. Not only that, we add fat. Now does that make sense? It's like buying a new car every year, each year getting a less powerful engine with a heavier car.

:confused:

caloso

Excellent! (I might have to steal this quote.)

cbhungry

Actually this Williams character is full of crap.

Lots of patients have lost weight by increasing their moderate activity as Koffee mentioned and have lost weight, improved their cholesterol, decreased insulin resistance and lowered blood pressure just by incorporating modest activity without the stress of trying to fit 1 hour of excercise into their lifestyles. I have seen this personally.

William's supposition is that the treadmill test is an erroneous measure of physical fitness. He refutes the Cooper institute data based on running numbers on a computer model and created hypothetical treadmill tests. Cooper's institute research model was a very good prospective clinical study. Williams did not take into account that they ensured these treadmill preformances were real due to corresponding change in self reported physical activity and also body fat composition measurements. The improved lifespan, as Blair continues to contend, "was due to improved living , not a glitch in measurement."

I do not trust computer modeling as a predictor of something as complex as human physiology because it cannot control for the variables I just mentioned. Look what computer modeling simulation tests did to predict the latest space shuttle's tragedy.

There is alot more research that shows that such moderate activity is quite beneficial. This press release will promote the "all or none" mentality that will impede the efforts of those who were trying to benefit themselves with small but significant activity.

jatkins679

Care to clarify all this? How does what the aerospace modeling people at NASA help to illustrate that Williams is incorrect?

cbhungry

Computer modeling has its limitations in prediciting complex systems such as predicting human mortality as it has limitations with a simpler system such as the space shuttle. (ie: their computers showed that the foam did not cause any significant harm and would not affect rentry etc.)

Just a poor attempt to provide a weak analogy.

He based his suppositions on on hypothetical treadmill measurement error without controlling for variables such as the self reported physical activity diaries, body fat composition etc. He committed the first fallacy of clinical medical research that is different from other sciences. I should know since as a chemist, it was easy to control for 1 or two variables in a chemical system. Sounds like he is a pure biostatician rather than a clinician who utilizes biostatistics.

Now if you want to see a good clinical study showing the effects of excercise and looking at many human variables as a consideration in their final conclusion
see the link.. https://www.medscape.com/viewarticle/450776

I trust the methodology of this one better, unfortunatly, it did not make it into the news.

DnvrFox

Sorry, that link required some sort of membership.

SamDaBikinMan

June 17, 2003



In This Article
Abstract and Introduction
Materials and Methods
Results
Discussion

--------------------------------------------------------------------------------

Tables
References

It Is Never Too Late: Change in Physical Activity Fosters Change in Cardiovascular Risk Factors in Middle-Aged Women


from Preventive Cardiology
Posted 04/01/2003
Jane F. Owens, DrPH, Karen A. Matthews, PhD, Katri Räikkönen, PhD, Lewis H. Kuller, MD, DrPH



Abstract and Introduction
Abstract
The purpose of the study was to determine the effect of physical activity, particularly change in physical activity over time, on cardiovascular risk factors in women. The 520 women in this analysis are part of an ongoing epidemiologic investigation of the effects of menopause on risk for cardiovascular disease; the investigation spans almost 20 years. The findings show that on average, physically active women have healthier risk factor profiles over time, and that as women change their activity level, their risk factor profiles change as well. Thus, for middle-aged women going through the menopausal transition, it is never too late to reduce their cardiovascular risk by increasing their activity level.

Introduction
Low levels of physical activity are associated with higher rates of both all-cause[1-4] and cardiovascular mortality.[4-7] Reports generally support similar findings in men[1] and women.[1,8] Physical activity is associated with lower incidence rates of stroke,[9,10] coronary heart disease (CHD),[11-13] diabetes,[14,15] hypertension,[16] osteoporosis,[17] and cancer.[18-21] Whether or not physical activity directly causes lower morbidity and mortality or is mediated by a more salubrious risk factor profile has not been determined, but most studies support a strong relationship between activity and risk factors for these diseases.

Cross-sectional studies consistently show a relationship between physical activity and a healthier cardiovascular risk factor profile. In general, physically active persons have lower systolic blood pressure (SBP), diastolic blood pressure (DBP),[22] triglycerides, and total and low-density lipoprotein cholesterol (LDL-C) levels and higher high-density lipoprotein cholesterol (HDL-C) levels.[23] In addition, physical activity is inversely related to serum insulin levels, suggesting increased insulin sensitivity among the more active.[24] Lower body weight and body mass index (BMI), as well as less body fat and a lower waist-to-hip ratio (WHR), are also characteristic of more active persons.[22,25] In general, similar patterns of risk factor/physical activity associations are found in men and women.

Prospective studies of the relationship between physical activity and risk factor change are much fewer in number. A review of clinical trials of physical activity and blood pressure concluded that increasing physical activity had the capacity to lower blood pressure in both hypertensive and normotensive persons.[26] In observational longitudinal studies, moderate physical activity reduced the risk of developing non-insulin-dependent diabetes mellitus (NIDDM).[14] In a large, population-based, observational study,[25] increasing physical activity over a 7-year period of time was associated with improved lipid and lipoprotein risk factor profiles and BMI in both men and women. In an observational study[27] of middle-aged women, decreasing physical activity over a 3-year period was associated with a greater decline in HDL-C.

Cross-sectional studies of physical activity and risk factors are unable to allow us to comment about cause and effect due to the potential for selection bias. Prospective observational studies traditionally have one measure of physical activity and one or more outcome measures evaluated at some time point removed from the initial measurement of activity. These studies do not take into account the well known variability in physical activity over the time. Thus, they are unable to capture concomitant changes between physical activity and risk factors for cardiovascular disease. The study described here has the advantage of multiple measurements of both physical activity and risk factors across almost two decades. Thus, it allows for the study of both the static relationship of physical activity and risk factors as well as the dynamic relationship between risk factor change and physical activity change in women. We hypothesize that more active women will have healthier risk factor profiles throughout the follow-up period, and that as women change their level of physical activity, there are concomitant changes in their risk factor profiles.



--------------------------------------------------------------------------------

SamDaBikinMan

Materials and Methods
Sample
Participants in this study were recruited beginning in 1983 for a longitudinal study of biologic and behavioral changes associated with natural menopause. At intake, all women (n=541) were premenopausal and between the ages of 42 and 50. Of the 541 women recruited to participate, 520 had sufficient data points for analysis in this study of physical activity. The women were recruited using driver license lists where home addresses were within an easy commute to the University of Pittsburgh. Eligibility criteria included premenopausal hormone status (menstrual bleeding in the preceding 3 months), being normotensive (DBP <100 mm Hg), no use of medications known to influence biologic risk factors, and no use of psychotropic or hormone medications. In general, the women were well educated, largely employed volunteers who were free of any chronic disease. All women were evaluated at study entry and then approximately 3-4 years later. The women were evaluated when they were postmenopausal (no menstrual bleeding for 12 months) and then approximately every 2 years after the first postmenopausal visit. After approximately 16 years of follow-up, seven women had died and 51 had withdrawn from the study.

Physical Activity Measurement
Physical activity was measured using the Paffenbarger Physical Activity Questionnaire. This assessment device, originally used in a longitudinal study of college alumni,[28] permits a calculation of kilocalories per week in expended energy. The calculation takes into account the energy expended in climbing flights of stairs, walking city blocks, and participating in sports or recreational activities. The questionnaire is now widely used in studies where assessment of physical activity is required.

Other Risk Factor Measurements
Blood pressures were taken in a clinic setting at the University of Pittsburgh. Two readings were taken by registered nurses using a random-zero muddler sphygmomanometer. The average of the two readings was used as the final reading. Weight and height were measured by a nutritionist or other clinic personnel. When participants were wearing normal street clothes, weight was measured to the 1/2 pound on a balance scale, and height was measured to the nearest 1/2 inch. Approximately two thirds of the way through the initial recruitment period, measurements of waist and hip were added to the protocol. These measurements were taken using a standard tape measure by clinic personnel. Waist was measured at the narrowest point mid-torso, and hip at the point of maximal protuberance of the gluteus maximus. Participants were queried about various health habits and personality and psychosocial factors. The number of cigarettes smoked per day was determined by interview or questionnaire at each time point. Alcohol intake was determined by questionnaire and was computed to reflect total grams of alcohol per day from all sources.

All blood samples were drawn when subjects were in a fasting state. Serum determinations of lipid and lipoprotein measurements were done in the Heinz Nutrition Laboratory in the Graduate School of Public Health at the University of Pittsburgh, a Centers for Disease Control standardization laboratory. Total cholesterol was measured using the enzymatic method[29] and HDL-C and HDL3-C by the precipitation method.[30] HDL2-C was calculated by subtracting HDL3-C from HDL-C. Triglycerides were measured enzymatically,[31] and LDL-C estimated by the Friedewald equation.[32] Plasma insulin levels were determined by radioimmunoassay, and glucose was measured with the Abbott glucose UV test (Abbott Laboratories, Abbott Park, IL) (Yellow Springs glucose analyzer [Yellow Springs Instruments, Yellow Springs, OH]).

Risk factor assessments were done on the following schedule: 1) premenopausal visit; 2) approximately 3-4 years later; 3) after amenorrhea for 12 consecutive months; and 4) approximately 2-3 years apart thereafter. Physical activity was assessed at each visit. This scheme allowed for a potential of nine separate assessments of risk factors and physical activity, depending upon how quickly women entered the menopause.

Physical activity data were available on 540 women at the premenopausal evaluation. At the 3-4 year follow-up, and at the following postmenopausal evaluations, physical activity and risk factor data were available on varying numbers of women, depending on the numbers who had been postmenopausal for that length of time. An average participant produced between 4 and 5 (range, 2-8) concurrent, repeated measurements of physical activity and risk factors after an average of 10.5 years (range, 1.0-13.9) in the study. Concurrent data were available on 503 women for blood pressure, 530 women for waist, height, and weight measurements, 499 for lipid and lipoprotein determinations, and 496 and 499 for insulin and glucose levels, respectively. These women formed the sample for the analyses of change in physical activity and in cardiovascular risk factors over time.

Statistical Analyses
To test whether changes in physical activity co-occur with any potential changes in risk factors over time, multilevel random coefficient regression analyses were carried out. Repeated risk factor measurements served as dependent variables (each factor tested in a separate model), and repeated measurements of physical activity served as a time-varying predictor variable for these models. This differentiated between-person (cross-sectional) and within-person (longitudinal) effects in these models, and also took into account the fact that persons have varying numbers of observations available for analysis. The physical activity data were person-centered, i.e., transformed to deviations from personal means, to account for between-person confounding in the within-person associations.

We expected changes in physical activity over time to be associated on a within-subject basis with concurrent changes over time in the risk factors. We also expected that those with higher average levels of physical activity across the study period would exhibit a more salubrious risk factor profile relative to those with a lower average level of physical activity. We used the maximum likelihood estimation method, and set up a variance component covariation matrix and a spatial, residual covariance matrix. In the longitudinal analyses of change, time to each assessment point from the study entry was used as a covariate. In addition, analyses were conducted with weight and alcohol consumption in the model, and among never-smokers only. The same strategy was used in the between-person cross-sectional analyses. Log transformations were conducted where appropriate.

SamDaBikinMan

Results
Premenopausal Risk Factor Levels
Table I shows the mean levels of risk factors for the women in our analysis at study entry. The number of women varied because of missing data, as changes were made in the protocol over time. SBP and DBP are low due to the exclusionary criteria established for the study. The average kilocalorie expenditure for 1 week was 1423 kcal (SD, 1640 kcal). Forty-seven percent of the women reported recreational sport activity in the preceding week. The majority of the activity was at a moderate level, and the most prevalent activity was walking.

Change in Risk Factors Across Time
Over time, the women, on average, reported an increase in their energy expended. Mean change scores for kilocalories and risk factors at selected time points are shown in Table II. The time points shown are approximately 3 years after study entry, and at assessments made at 1, 5, and 8 years after menopause. Also shown in Table II are the coefficients of variation, which indicate the extent of variability in the measurement across all available data points. The variability in kilocalories expended is evidence of the fact that over time, women experience changes in their physical activity levels. However, the changes in terms of kilocalories are, on average, rather modest, and are consistent with the amount of change in activity for the first time that risk factor change and activity change were evaluated in this group.[27]

Average and Concurrent Associations Between Physical Activity and Risk Factors
In the between-person analyses shown in Table III, women who were, on average, more active across the study period had lower average fasting insulin, triglyceride, blood pressure, waist circumference, and weight levels compared to women who were, on average, less active across the study period. In addition, more active women had higher HDL-C and HDL2-C levels (all, p<0.002). When weight was controlled, the association between higher activity and lower triglycerides became marginally significant (p=0.08). All other associations remained significant (all, p<0.02). Adjustment for alcohol intake or restriction to only nonsmokers at all time points did not yield different results. These results are consistent with the findings at study entry.[23]

In Table IV, the mean level of risk factors measured across all available time points is shown by tertile of kilocalories, similarly measured across all available time points. A test for linear trend showed that SBP (p=0.06), DBP (p=0.01), and fasting insulin (p=0.001) decreased across tertiles of physical activity. Both HDL-C and HDL2-C increased significantly across activity groups (all, p<0.003). In terms of the anthropometric measurements, weight, BMI, and waist circumference showed a significant decrease across the activity groups (all, p<0.001). This serves to further illustrate the trend for a more salubrious risk factor profile across time in more physically active women.

Within-person associations between kilocalories expended weekly and risk factors are also shown in Table III. Results show that as a woman increases her level of physical activity, her levels of fasting insulin and triglycerides, BMI, and weight and waist circumference decrease significantly (all, p<0.03). There was a tendency (p=0.06) for SBP to decrease as activity levels increased, but lipid and lipoprotein levels were unaffected by change in activity. Results were unaffected after statistical controls for alcohol consumption and smoking.

SamDaBikinMan

Discussion
This study confirms that physically active women have risk factor profiles that are associated with lower cardiovascular morbidity and mortality. Furthermore, it shows that over time, middle-aged women who increase their physical activity levels have concomitant improvements in their risk factor profiles. This gives support to the hypothesis that physical activity is effective in preserving and improving the health and well-being of middle-aged women.

Over multiple cross-sectional measurements across the 16 years of observation in this study, higher activity levels were associated with lower blood pressure, a healthier lipid profile, lower fasting insulin levels, and lower weight, BMI, and waist measurement. Similar relationships were seen in the sample at study entry, when all the women were premenopausal and 47 years of age on average, and over time these relationships remained unchanged.

Furthermore, in the longitudinal analyses, when women increased their activity, their risk factor profiles improved; decreasing activity was associated with deleterious changes in risk factor profiles. Having multiple measurements available for analyses lends confidence to the hypothesis that changing physical activity can lower risk for disease. Kaplan and colleagues[4] employed a similar strategy in analyzing the effect of activity and all-cause and cardiovascular disease mortality. They had three time points available for analyses, and found that the effects of physical activity were much stronger when all time points were used than when one initial assessment of activity was used as a predictor.

In this study, there was a strong relationship between weight and physical activity in both the longitudinal and cross-sectional analyses. Given the known association between weight and blood pressure, and the observed relationship between activity and weight, being active may play an important role in reducing the cardiovascular and cerebrovascular sequelae of elevated blood pressure.

The relationships between lipids and lipoproteins and physical activity seen in other studies were not confirmed in the within-person analyses in this study. However, there was a very interesting finding of a relationship between triglycerides and activity, controlling for age and weight, that has not been noted before. Elevated triglyceride levels have been related to coronary artery disease in some studies,[33] although the evidence is not as strong as the risk associated with total cholesterol, LDL-C, or HDL-C. Nonetheless, in studies where attempts have been made to identify ways to elucidate the risk basis of elevated triglycerides, there is good evidence that there is greater risk for cardiovascular disease[34,35] that is largely independent of age, weight, and alcohol intake.

Greater WHR and higher BMI have been identified as risk factors for heart disease. It has also been shown that waist circumference is a risk factor for cardiovascular disease and for NIDDM.[36] Waist circumference is a measure of central adiposity, and has been shown to be superior to WHR in dual-energy x-ray absorptiometric,[37] magnetic resonance imaging,[38] or computerized tomographic[39] determination of central adiposity. In this study, waist circumference was significantly smaller in women who, over time, increased their physical activity level, as well as in more physically active women in the cross-sectional analyses. The cross-sectional relationship is independent of the women's weight.

Physical activity level and increase in activity level over time are significantly related to fasting insulin levels, even when age, weight, and alcohol intake are controlled for in the analyses. Elevated insulin levels are a marker for decreased insulin sensitivity, a predictor of NIDDM. There is considerable interest in physical activity as a means of preventing NIDDM, and there are supportive studies, both cross-sectional and prospective. Obesity is a major risk factor for NIDDM, so interventions designed to reduce or prevent overweight or obesity have been of major interest in this field. Unfortunately, dietary interventions and exercise programs are fraught with adherence problems that make them of somewhat limited value. Therefore, it is of considerable interest to note, in this study, the strong relationship between a moderately active lifestyle and a lower insulin level in women, which is independent of age and weight.

The sample recruited for this study initially excluded women who had any chronic disease, as indicated by self-report or use of certain medications. Therefore, they represented a healthy segment of the population. Furthermore, they were, in general, well educated and primarily Caucasian. These attributes limit the ability to extrapolate our findings to other less healthy, less educated, and non-Caucasian populations. Studies of physical activity and cardiovascular health should be undertaken with specific intent to target non-Caucasian and high-risk women to determine if activity is similarly beneficial in these groups.

It should also be noted that this study was not designed to explicitly measure the effects of physical activity on the metabolic syndrome. However, many of the risk factors examined in this sample are covariates with change in physical activity: triglycerides, insulin, weight, and waist circumference are a part of a cluster of risk factors that, taken together, are thought to indicate an altered metabolic syndrome that is associated with greater cardiovascular risk.[40] To our knowledge, this is the first time this set of risk factors has been reported to change over time with physical activity in middle-aged women.

Taken together, the findings of this study show that the cardiovascular risk factors of elevated blood pressure, serum triglycerides, and insulin, and central adiposity -- all part of a frequently seen clustering of metabolic abnormalities -- are sensitive to the influence of changing physical activity in middle-aged women. This study also provides evidence that over time, women are able to maintain or even increase their physical activity as they progress through middle age, dispelling the myth that aging is necessarily associated with an overall decline in activity level. The potential for moderate physical activity to have a role in modifying this clustering of metabolic risk factors is exciting and worthy of further attention.


Funding Information

This research was supported by the Healthy Women Study (NIH grant HL28266) and the Pittsburgh Mind-Body Center (NIH grants HL65111 and HL65112).

Reprint Address

Address for correspondence: Jane F. Owens, DrPH, Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213

SamDaBikinMan

The above four posts are the property of Medscape and if they don't like me posting it here then I'll see ya'll in prison....

Pete Clark

Absolutely.

But I agree with the idea that our recommended guidelines for physical activity are on the low side. As Koffee suggested, if we incorporated exercise into our daily activities more, we'd easily get plenty of good exercise and wouldn't need to set aside additional time for it.

greg360

That's the heart of the matter.
It is no coincidence that the overexaltation of professional athletes has happened right in sync with the rise in obesity of spectators.
The media has done an effective, if surreptitious, job of telling people that if you ain't a bigshot you ain't sh*t, so why try?
But if you can't be like Magic Johnson you can at least feel like him if you watch our flattering commercials and drink this beer, drive that car, wear those shoes...
Hmmmm... if Bianchi adopted the same marketing techniques as Budweiser, they'd make a fortune.
Imagine Super Bowl commercials saturated with bikes instead of brews.
Oh wait, bikes require sustained physical effort to get results and Buttweiser does not.
Never mind. My bad.

belfast-biker

Wow, Sad.