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New Theory on Coronavirus - the Bradykinin Hypothesis

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New Theory on Coronavirus - the Bradykinin Hypothesis

 
Old 10-15-20, 08:40 PM
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ropetwitch
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New Theory on Coronavirus - the Bradykinin Hypothesis

Folks,

I have read a latest medical update on Coronavirus - the Bradykinin Hypothesis. I am not sure how accurate their findings are but somehow the study is a good one. In this way they can formulate a targeted treatment of Covid-19.

What are thoughts in this guys? Care to share Thanks
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Old 10-15-20, 09:00 PM
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See this thread started Oct 4.
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Old 10-17-20, 05:22 AM
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Originally Posted by ropetwitch View Post
Folks,

I have read a latest medical update on Coronavirus - the Bradykinin Hypothesis. I am not sure how accurate their findings are but somehow the study is a good one. In this way they can formulate a targeted treatment of Covid-19.

What are thoughts in this guys? Care to share Thanks
I started the previous one but lets have it with another.

How accurate is it? It's effectively the second coming of Christ (its very accurate), and because its accurate, its being ignored. An accurate hypothesis is one that explains all the symptoms and the bradykinin hypothesis does just that. Also this is no minor crackpot theory from a Maverick Scientist. They used the Worlds second fastest super computer for a whole WEEK of number crunching to come up with the data.
Is anyone really paying any attention? No.
You know why? This ain't Socialism baby, its Capitalism and the capitalist money is already betting on a vaccine so its not about to give in just because someone else solved the problem.
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Old 10-17-20, 01:48 PM
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Originally Posted by AnthonyG View Post
Yeah no. There's plenty of money to be made from vaccines when governments bend over backwards to provide pharmaceutical companies with blanket exemptions from liability. Also I clearly stated that political capital was at stake as well.
Anyway I digress.
I'm not anti-vaxx, I'm pro Science. When people claim that you have to be either pro-vaccine or anti-vaccine then you know that there is no Science involved in the debate.
What Science do you have in the first place to demonstrate that a vaccine was the correct treatment regime to pursue for COVID-19?
This is the beauty of the "Bradykinin hypothesis" that I provided a link to.
Someone was doing REAL Science. They made an observation, they asked a question, they proposed a hypothesis, they tested it and then they published the results.
And because it was real Science its stands more than a reasonable chance of being ignored. I can't see a major pivot away from the pursuit of a vaccine at the moment even though the Bradykinin hypothesis is pointing towards some other existing drugs and even simple vitamin D as the appropriate treatment.

You're false dichotomizing all over the place here. The article makes very clear that this is, at this point, a hypothesis generated from data, not as yet proven. It's clearly a promising idea, and I'm sure there's going to be a lot of testing of new treatments based on this hypothesis. I don't think anyone is seriously arguing that all eggs should be placed in either the treatment vs. vaccine baskets. This is a novel virus spreading more rapidly than we can control. The only logical approach is to try a variety of diverse approaches to treatment and immunity and to see which pan out.

Right now, the computer has spit out a solution which appears to fit most if not all the data. Now is when we figure out if that is an accurate description of what is really going on. You don't need politics or self-interest to explain why that isn't instantaneous.

We're trying to develope vaccines because we have the tools to do that much more rapidly than could be done in the past. This being a novel virus, no one can say for certain or not whether it's actually possible. The reason we pursue it is because immunity is inherently better than having to treat the illness. I don't know about you, but I'd much rather avoid getting the disease entirely than going through the almost certainly expensive and possibly dangerous process of having the disease cured. This is self-evident so your whole argument is rather silly.

TL/DR: no one in their right mind is proposing we don't try both development of vaccines and treatments.
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Old 10-17-20, 01:53 PM
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Originally Posted by AnthonyG View Post
I started the previous one but lets have it with another.

How accurate is it? It's effectively the second coming of Christ (its very accurate), and because its accurate, its being ignored. An accurate hypothesis is one that explains all the symptoms and the bradykinin hypothesis does just that. Also this is no minor crackpot theory from a Maverick Scientist. They used the Worlds second fastest super computer for a whole WEEK of number crunching to come up with the data.
Is anyone really paying any attention? No.
You know why? This ain't Socialism baby, its Capitalism and the capitalist money is already betting on a vaccine so its not about to give in just because someone else solved the problem.

Also, what proof do you have that it's being ignored? This is a new idea that needs to be tested by real world observation. You've just skipped that part.
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Old 10-17-20, 01:54 PM
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Originally Posted by ropetwitch View Post
Folks,

I have read a latest medical update on Coronavirus - the Bradykinin Hypothesis. I am not sure how accurate their findings are but somehow the study is a good one. In this way they can formulate a targeted treatment of Covid-19.

What are thoughts in this guys? Care to share Thanks
It looks good and I hope they're right.
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Old 11-03-20, 04:54 AM
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Originally Posted by AnthonyG View Post
I started the previous one but lets have it with another.

How accurate is it? It's effectively the second coming of Christ (its very accurate), and because its accurate, its being ignored. An accurate hypothesis is one that explains all the symptoms and the bradykinin hypothesis does just that. Also this is no minor crackpot theory from a Maverick Scientist. They used the Worlds second fastest super computer for a whole WEEK of number crunching to come up with the data.
Is anyone really paying any attention? No.
You know why? This ain't Socialism baby, its Capitalism and the capitalist money is already betting on a vaccine so its not about to give in just because someone else solved the problem.
Does this research have the government's support? I believe that this is an accurate hypothesis, my only question is what are they doing with it right now? Any progress?
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Old 11-03-20, 05:08 AM
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Originally Posted by ropetwitch View Post
Does this research have the government's support? I believe that this is an accurate hypothesis, my only question is what are they doing with it right now? Any progress?
What on earth does the Government have to do with anything?
Our modern western system of medicine doesn't start with any Scientific research/input from a Government.
Our modern western system, STARTS, as a PRIVATE, money making, commercial venture, and if a private company can't see any profit in it, they don't develop it.
Governments only have a say quite late in the process by saying yay or nay to products that private companies have already spend billions of dollars on developing so at this stage the pressure is seriously on to find a way to say, YES.
Yet, nothing gets this far without a company seeing a lucrative profit in it.

What on earth does Science or healing people for the "common good", got to do with anything i've just written above?
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Old 11-03-20, 06:46 AM
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Originally Posted by AnthonyG View Post
What on earth does the Government have to do with anything?
Our modern western system of medicine doesn't start with any Scientific research/input from a Government.
Our modern western system, STARTS, as a PRIVATE, money making, commercial venture, and if a private company can't see any profit in it, they don't develop it.
Governments only have a say quite late in the process by saying yay or nay to products that private companies have already spend billions of dollars on developing so at this stage the pressure is seriously on to find a way to say, YES.
Yet, nothing gets this far without a company seeing a lucrative profit in it.

What on earth does Science or healing people for the "common good", got to do with anything i've just written above?
Dude, you live in Australia, so you know there are still some Universities around the world that do research without the private sector, then commercialise it later, maybe take the tinfoil hat off....
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Old 11-03-20, 06:52 AM
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Originally Posted by Trevtassie View Post
Dude, you live in Australia, so you know there are still some Universities around the world that do research without the private sector, then commercialise it later, maybe take the tinfoil hat off....
Really? That's a mighty flimsy branch to hang all your hopes on. China is more likely to use "real" Science than a Western Country is and I'm no fan of Chinese leadership at the moment.
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Old 11-03-20, 12:54 PM
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Originally Posted by AnthonyG View Post
What on earth does the Government have to do with anything?
Our modern western system of medicine doesn't start with any Scientific research/input from a Government.
Our modern western system, STARTS, as a PRIVATE, money making, commercial venture, and if a private company can't see any profit in it, they don't develop it.
Governments only have a say quite late in the process by saying yay or nay to products that private companies have already spend billions of dollars on developing so at this stage the pressure is seriously on to find a way to say, YES.
Yet, nothing gets this far without a company seeing a lucrative profit in it.

What on earth does Science or healing people for the "common good", got to do with anything i've just written above?
Not true. The NIH (National Institute of Health in the USA, ie Government) spends a large amount of money in research.

"Did you know that NIH is the largest public funder of biomedical research in the world, investing more than $32 billion a year to enhance life, and reduce illness and disability? NIH funded research has led to breakthroughs and new treatments, helping people live longer, healthier lives, and building the research foundation that drives discovery."
https://www.nih.gov/grants-funding
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Old 11-03-20, 04:12 PM
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Yeah, the NIH is a huge factor here in the US, along with generally constructive and sound research for public health policy (and hopefully will be again after this administration). Years ago while stationed in the Washington DC our group did some grunt work in conjunction with immunology research for the NIH, along with other stuff for oncology, transplantation, etc.
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Old 11-17-20, 09:19 PM
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Originally Posted by CycleryNorth81 View Post
Not true. The NIH (National Institute of Health in the USA, ie Government) spends a large amount of money in research.

"Did you know that NIH is the largest public funder of biomedical research in the world, investing more than $32 billion a year to enhance life, and reduce illness and disability? NIH funded research has led to breakthroughs and new treatments, helping people live longer, healthier lives, and building the research foundation that drives discovery."
https://www.nih.gov/grants-funding

Oh wow, it's my first time hearing of it, I only knew of big-spending of the US Government in their Military.
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