Glucosamine, yea or nay?
#51
Full Member
https://nyti.ms/2k7bOT7
This study indicates that placebos are more effective. Not necessarily a bad thing as if you feel you are being helped then you are in some sense. Still, if the cost of supplements were a burden, I'd be on the side of studies.
Good health.
This study indicates that placebos are more effective. Not necessarily a bad thing as if you feel you are being helped then you are in some sense. Still, if the cost of supplements were a burden, I'd be on the side of studies.
Good health.
#52
Senior Member
I took glucosamine for decades for a knee that had to be scoped. I also have a hip with arthritis. Then a couple of years ago I stopped taking it. I noticed no difference afterwards. Count me as a statistical sample of one.
#53
Farmer tan
I've tried on and off for a few years.
Didn't seem to help back, ankle, knee, or toe.
It did give me stomach ache.
On the other hand, high quality curcumin and full strength ginger juice seem to help.
Didn't seem to help back, ankle, knee, or toe.
It did give me stomach ache.
On the other hand, high quality curcumin and full strength ginger juice seem to help.
#54
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This is timely. I was discussing glucosamine with a friend this morning who is trying her best to put off knee replacement surgery. Stupid question:
It seems to me that rather than argue about whether it works or not, simply try it and see. And if the placebo effect is at play, who cares? As long as you're in less pain, your good. Well ... Unless there are negative side effects.
Which brings me to my question ... Are there any studies pointing to negative side effects associated with taking glucosamine?
It seems to me that rather than argue about whether it works or not, simply try it and see. And if the placebo effect is at play, who cares? As long as you're in less pain, your good. Well ... Unless there are negative side effects.
Which brings me to my question ... Are there any studies pointing to negative side effects associated with taking glucosamine?
#55
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Glucosamine is very safe to supplement and its most common side-effect is flatulence.
The General Safety writeup:
Doses of up to 2000mg a day have been deemed most likely safe for long-term side effects in a risk assessment[187] while multiple meta-analysis' conducted on the usage of Glucosamine (usually as Sulphate) at doses of up to 1,500mg (with or without the inclusion of up to 1,200mg Chondroitin Sulphate) note that these doses are not associated with side-effects that are more prevalent than placebo treatment.[42][117][34][43] In regards to position statements on Glucosamine by the Osteoarthritis Research Society International (OARSI[14][15]), the European League Against Rheumatism (EULAR[16][17]) the American College of Rheumatology[18] and the UK National Institute for Health and Clinical Excellence[13] Glucosamine is generally recognized as a safe nutritional intervention (the positions seem split on the efficacy thereof, but safety appears to be consensus).
Glucosamine supplementation at or around the most commonly used dosage of 1,500mg appears to be quite a safe supplemental intervention as assessd by previous human trials and toxicological studies
Glucosamine supplementation at or around the most commonly used dosage of 1,500mg appears to be quite a safe supplemental intervention as assessd by previous human trials and toxicological studies
Although there does not appear to be a large adverse interaction between glucosamine and diabetes (some schools of thought believe that glucosamine induces insulin resistance, which doesn't appear to be that reliable in humans after oral ingestion) it still seems to be prudent to ask a medical doctor about using glucosamine if one is pre-diabetic or diabetic
Although glucosamine per se is not allergenic, other bioactives from its source (shellfish) may be found in some dietary supplements and thus persons with shellfish allergies should take caution in using glucosamine supplementation
Although glucosamine per se is not allergenic, other bioactives from its source (shellfish) may be found in some dietary supplements and thus persons with shellfish allergies should take caution in using glucosamine supplementation
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"I had a great ride this morning, except for that part about winding up at work."
Bikes so far: 2011 Felt Z85, 80's Raleigh Sovereign (USA), 91 Bianchi Peregrine, 91 Austro-Daimler Pathfinder, 90's Trek 730 Multitrack, STOLEN: 80 Schwinn Voyageur (Japan)
#56
Senior Member
My wife has osteo arthritis and Celedrin seems to be very effective in giving relief. She has been on it for a month and has really noticed a big difference. My wife is very active..works out everyday.
Mike A.
Mike A.
#57
Full Member
Glucosamine/Chondroitin pills seem to keep my joints from popping from simple movements - without them, and after regular vigorous exercise or cycling, I can make my ankles pop from a simple side-to-side motion, and my knees and wrists will pop more frequently. The cost of taking them consistently, however, is prohibitive; I haven't taken them for a few years, and just live with the popping.
#58
Senior Member
To me, it has always been a preventive measure to reduce the rate of deterioration in healthy joints. Using it to try to repair damage already done is unlikely to be helpful.
FWIW, I have take it regularly for at least the past decade. My joints were healthy to start with and appear to have remained that way since.
If heredity has an influence, I am doing better than my parents who both showed signs of joint deterioration starting at my current age.
Regular exercise/activity that helps strengthen supporting ligaments, tendons and muscles also might be helpful.
FWIW, I have take it regularly for at least the past decade. My joints were healthy to start with and appear to have remained that way since.
If heredity has an influence, I am doing better than my parents who both showed signs of joint deterioration starting at my current age.
Regular exercise/activity that helps strengthen supporting ligaments, tendons and muscles also might be helpful.
#59
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Works for me. I take a pill with Glucosamine, Chondroitin, MSM, turmeric (curcumin) and propolis. It helps my body aches and pains all over and has been helping with a worn knee and hip. Can only prove what I know, and only to myself.
#60
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No. That stuff gave me the ****s something awful. Omega 3 supplements seem to help my joints as well as keeping my weight down.
#61
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Switched from the hydrochloride to the sulfate about a month ago.
It seems to make a difference now.
It seems to make a difference now.
#62
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I've settled on Osteo-Bioflex as well. Does it help? I have no statistical proof. Then again, I started it after other glucosimin supplements. And, after left total knee replacement. I was trying to save my other knee. At least my shoulder feels better. My right knee is on the path to replacement as well. Had it scoped last summer. Looking for the gel now... I have other issues that are resolving.
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