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Glucosamine, yea or nay?

Old 01-01-17, 10:15 AM
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one4smoke
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Glucosamine, yea or nay?

What do you fellas think about glucosamine, for helping with worn cartilage of our joints, especially the knees?

Awhile back I was reading a post where someone said there were a couple of different kinds, and recommended one over the other, but I don't remember which one and can't find the post. Any thoughts on this?

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Old 01-01-17, 10:17 AM
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It Never helped me.

I don't know Why but Vitamin E works for me.
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Old 01-01-17, 10:38 AM
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I don't think that it helps. I've never noticed any difference. Fish oils may offer some help but I can't say I've noticed much. I suspect your overall diet and 'constitution' (to use an old term) may determine any benefit.

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Old 01-01-17, 10:48 AM
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I switched over to Celadrin and - for me - it has worked wonderfully. Never noticed any effect from gluc/chondroitin.
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Old 01-01-17, 10:53 AM
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Didn't work for me.
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Old 01-01-17, 11:11 AM
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Sorta worked for me back before I started dialysis. Since then, I haven't needed it. Helped my old arthritic cat for a while, though....
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Old 01-01-17, 02:13 PM
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I've been taking it since 2001; the times I stopped for a short time were wracked with stiffness and limitations. It Osteo-BiFlex for me from now on. Fish Oil helps, too, I discovered.

Bicycling Magazine's Fitness Chick(?), Selene Yeager, tried it on her old dog, and it helped. Since dogs have no "placebo effect" like that, it seemed to be good evidence for her when asked.

NOTE: You can get JUST glucosamine, or a formula mix with any/all of the following: MSM, hyaluronic acid, condroitin, and probably a couple I'm forgetting right now. Condroitin, IMO, is a necessity. HA is wrong for me.
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Old 01-01-17, 02:37 PM
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I've been taking glucosamin sulfate for years. I can't prove conclusively it helps but fell better when using it.
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Old 01-01-17, 02:57 PM
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Helped me, my wife, and our cat. Been taking it for maybe 20 years. Glucosamine sulfate shows some benefit in trials while glucosamine hydrochloride provides no benefit. Chondroitin doesn't work either. MSM has also shown some efficacy, so it's hard to say whether it's the glucosamine or the sulfur that's providing the benefit. Works anyway, but not for everyone, which I take to mean that not everyone's knee pain has the same origin. We now take a glucosamine/MSM combo cap to simplify things.
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Old 01-01-17, 06:15 PM
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Tried it for years for minor knee pain. Pain got no better or worse when using and got no better or worse when I stopped using. It's worth a try if you can get a bargain price on it. It's a bit of a drain on the wallet.
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Old 01-01-17, 06:25 PM
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I use it, combined with magnesium and something else. I like it and it likes me.
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Old 01-01-17, 07:38 PM
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It definitely helps my knees. I've tested stopping/starting a few times and there is a difference for me. I use the gluc/chond/msm combo. Tart cherry juice also helps with the arthritis in my fingers -- swelling visibly decreased in just a few days.

Why it works for some, not for others, and can't be shown to help in large trials is a mystery.
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Old 01-02-17, 12:00 AM
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Originally Posted by Carbonfiberboy View Post
Helped me, my wife, and our cat.
How do you get a cat to take it?

Do you have to pop a pill down its throat or I dunno . . . .?
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Old 01-02-17, 06:53 AM
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Originally Posted by one4smoke View Post
What do you fellas think about glucosamine, for helping with worn cartilage of our joints, especially the knees?

Awhile back I was reading a post where someone said there were a couple of different kinds, and recommended one over the other, but I don't remember which one and can't find the post. Any thoughts on this?
My ex mother-in-law swears by the stuff. Said it worked wonders for her hips, and helped a little bit with her knees (before she had them both replaced). As for my knees and right hip, I didn't feel any improvement during the almost three months I tried it.




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Old 01-02-17, 08:08 AM
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Whether or not glucosamine works or not is pretty controversial. Our vet always suggests it for our old arthritic cats (we have/have had several), but in my experience, veterinarians have a built-in conflict of interest, because they not only recommend but also sell veterinary medications.

I'm like an old pure-bred dog - I have hip dysplasia. And the quote below is from International Hip Dysplasia Institute (International Hip Dysplasia Institute |) site. (YMMV)

"Glucosamine and chondroitin: Randomized controlled studies have shown that these supplements do not promote the growth of cartilage or improve joint health. It is still possible to buy these supplements, but they will not improve the health of your hip joint. People who are allergic to shellfish should not take glucosamine. Glucosamine and chondroitin can interfere with blood-thinning medicines."
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Old 01-02-17, 09:13 AM
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Originally Posted by MinnMan View Post
Whether or not glucosamine works or not is pretty controversial. Our vet always suggests it for our old arthritic cats (we have/have had several), but in my experience, veterinarians have a built-in conflict of interest, because they not only recommend but also sell veterinary medications.
How do you get your cats to take the glucosamine?

Is it in tablet form and you hold your cat's head and pop it down its throat?
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Old 01-02-17, 09:25 AM
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Originally Posted by ColonelSanders View Post
How do you get a cat to take it?

Do you have to pop a pill down its throat or I dunno . . . .?
We use Cosequin, which is 2-piece caps. He eats wet food, so we open a cap and mix it into his food. He doesn't seem to notice the difference. We give him 2 caps/week.
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Old 01-02-17, 09:27 AM
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Originally Posted by ColonelSanders View Post
How do you get your cats to take the glucosamine?

Is it in tablet form and you hold your cat's head and pop it down its throat?
Different cats require different strategies.

We have one very cooperative cat who raises his head and purrs when we give him pills. I open his jaw, put the pill on his tongue, close his mouth, and he swallows.

We had another cat who would eat wet cat food with a crushed up pill. Normally our cats only get dry food.

We have a third cat who will not take a pill at all. We would be severely bloodied if we tried. He's too young to need glucosamine (if indeed, glucosamine does anything other than enrich the vet). For other medications, we can manage to get a liquid squirted into his open mouth. Haven't tried it with glucosamine, but it could be possible to make a suspension and administer with a plastic syringe.

My sister has a cat who takes pills with pill pockets, but we have never had any luck with those.
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Old 01-02-17, 09:53 AM
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I was having knee issues about 15 years ago, and Glucosimine/MSM and chondrontin were recommended to me by a friend. (I was doing a lot of running and playing basketball.) My knee issues went away in about 3 weeks, and I've been afraid to stop taking them ever since! I am on a minimal daily dose.
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Old 01-02-17, 10:06 AM
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Originally Posted by one4smoke View Post
What do you fellas think about glucosamine, for helping with worn cartilage of our joints, especially the knees?

Awhile back I was reading a post where someone said there were a couple of different kinds, and recommended one over the other, but I don't remember which one and can't find the post. Any thoughts on this?
I use glucosamine chondroitin triple strength,Walgreens.Went off of it twice,sharp pain in wrist came back.It does nothing for my knee pain.

Last edited by Shamrock; 01-02-17 at 10:22 AM. Reason: Goof up
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Old 01-02-17, 10:15 AM
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I've been taking Osteo Bi-Flex (Glucosamine 1500mgand, Chondroitin MSM 1100mg, botswellia serrata extract 100mg) for a couple of years now, 1 tablet/day. I've found that I don't have quite as much knee pain, and my finger joints don't swell as much in the Wintertime.

Of course, Your results may vary, and all that legalese crap...
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Old 01-02-17, 10:25 AM
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Originally Posted by Carbonfiberboy View Post
We use Cosequin, which is 2-piece caps. He eats wet food, so we open a cap and mix it into his food. He doesn't seem to notice the difference. We give him 2 caps/week.
Yeah, actually, my memory was inaccurate. The cat who ate wet food+drugs was eating cosequin powder from capsules. We didn't have to crush up pills.
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Old 01-02-17, 11:02 AM
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Originally Posted by Currmudge View Post
Bicycling Magazine's Fitness Chick(?), Selene Yeager, tried it on her old dog, and it helped. Since dogs have no "placebo effect" like that, it seemed to be good evidence for her when asked.
The problem is, dogs also don't have any ability to confirm Ms. Yeager's anecdote; there's no unequivocal feedback narrative (what psychologists call "heterophenomenology") from the patient, just Ms. Yeager's observations, which could be confirmation bias -- a placebo effect of sorts -- on her part.
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Old 01-02-17, 01:02 PM
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Originally Posted by Carbonfiberboy View Post
We use Cosequin, which is 2-piece caps. He eats wet food, so we open a cap and mix it into his food. He doesn't seem to notice the difference. We give him 2 caps/week.
Thanks for the info.

I don't have a cat that needs it, but I was wondering if the time came, how to go about it.

Originally Posted by MinnMan View Post
Different cats require different strategies.

We have one very cooperative cat who raises his head and purrs when we give him pills. I open his jaw, put the pill on his tongue, close his mouth, and he swallows.

We had another cat who would eat wet cat food with a crushed up pill. Normally our cats only get dry food.

We have a third cat who will not take a pill at all. We would be severely bloodied if we tried. He's too young to need glucosamine (if indeed, glucosamine does anything other than enrich the vet). For other medications, we can manage to get a liquid squirted into his open mouth. Haven't tried it with glucosamine, but it could be possible to make a suspension and administer with a plastic syringe.

My sister has a cat who takes pills with pill pockets, but we have never had any luck with those.
Good stuff, thanks for all those different stories about your kitties.
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Old 01-02-17, 03:18 PM
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Originally Posted by Bob Ross View Post
The problem is, dogs also don't have any ability to confirm Ms. Yeager's anecdote; there's no unequivocal feedback narrative (what psychologists call "heterophenomenology") from the patient, just Ms. Yeager's observations, which could be confirmation bias -- a placebo effect of sorts -- on her part.
So a dog cannot demonstrate relief from a limitation by their behavior? Bye. We're done.
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