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20 mg lovastatin and performance suffers

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20 mg lovastatin and performance suffers

Old 07-28-09, 07:37 PM
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20 mg lovastatin and performance suffers

The doc put me on statins to lower my chloresterol.
That was about 3 weeks ago.

My ride performance has gone down hill.

I am easily winded.
Speed that I could hold at 75% MHR now takes 85% or more.
If I ride at 75% MHR speed is down 1.5 to 2 mph.

WTF?
Thoughts
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Old 07-28-09, 07:41 PM
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Tell your doctor to go stick it. High cholesterol is pretty much the biggest scam in the health business.
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Old 07-28-09, 07:43 PM
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paging Dr. Pete.
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Old 07-28-09, 07:49 PM
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Originally Posted by mondaycurse View Post
Tell your doctor to go stick it. High cholesterol is pretty much the biggest scam in the health business.

I think your reduced performance could be medication related, but may not be. Discuss this with your doctor. Also, to be an informed statin user, you could determine your 10 year NCEP (National Cholesterol Education Program) risk for a stroke or heart attack using a validated method available on the internet. Give this value to your healthcare provider. Look on Google and use "10 year NCEP risk calculator" as the search phrase. You have to enter your age, sex, systolic blood pressure, smoking status (hopefully nonsmoker!), total cholesterol, and HDL level (prior to starting the statin). This method is not valid for diabetics, however (as they are at relatively higher risk and are usually in need of taking the Statin).

If you are young, and do not smoke or have high blood pressure, and actually have a decent HDL, your doctor may be persuaded to let you go off the Statin. It's always best to follow your doctor's instructions, but sometimes doctors may not realize that you actually are not at high risk. If they are reasonable they will not resent you taking an interest and discussing this information with them.

Good luck.
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Old 07-28-09, 08:19 PM
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You can try a natural statin, red yeast rice, which shouldn't hurt your performance.
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Old 07-28-09, 08:22 PM
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I faced the same issues. My chol was moderately elevated, in the 220-230 range unmedicated. I tried diet, i already exercise lots, i ate a lot of oat meal and oat bran but didn't bring it down much. I first tried lipitor, and same thing, I felt it was affecting my performance. Quit lipitor, then tried crestor, only 10 mg three times a week, which was better but still I felt was affecting me, making me slower, tire easily, etc. The other issue is that my bilirubin(liver pigment) level on lipitor was the highest number it could be, 1.2 i think, and still be considered normal. Off lipitor it was 0.4. Then I read a long thoughtfully written article in business weekly, talking about exactly what a load of bs the evidence that statins really help anyone who has not had a heart attack really is. So now I am staying off meds basically march through september, then I will recheck my levels after cycling season slows down, and go back on the crestor if i need to. By the way the 10 mg three times a week did bring my level down a lot.
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Old 07-28-09, 08:39 PM
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There is quite a lot of evidence that statins can reduce all cause mortality in patients without histories of coronary artery disease. This data comes from the TexCAPS/AFCAPS studies performed in the early 90s. However, in these trials ( they were airforce studies) 90% of patients were men, so this data may not apply to women.
In patients at high risk ( 1-2 % per year TIMI risk score) or with established coronary disease, there is no questions that they are beneficial. They reduce inflammation besides lowering cholesterol, and stabilize plaque both in cardiovascular system and other vascular beds including the brain and kidneys. THey reduce the risk for strokes in patients with CAD and with TIAs/ strokes, and they may be protective against development of ALzheimer's or other dementias.
They are not perfect however. The original statin ( Lovastatin now called Mevacor) when given to animals in high doses caused enlargement of the gut cells' Endoplasmic reticulum and this was mistaken for bowel lymphoma. No other cancers have been linked. The statins can also cause a myositis in some patients, manifested by muscle inflammation and breakdown. This decreases the ability of muscle to function appropriately and is probably responsible for your decrease in performance. In my practice, I usually check a CK or myoglobin level if symptoms such as these occur, and if only midly elevated I start the patient on Coenzyme Q-10 ( Uiquinone). This is a vitamin which has been shown to be present at low levels in patients on statins.
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Old 07-28-09, 09:06 PM
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Originally Posted by calves2997 View Post
There is quite a lot of evidence that statins can reduce all cause mortality in patients without histories of coronary artery disease. This data comes from the TexCAPS/AFCAPS studies performed in the early 90s. However, in these trials ( they were airforce studies) 90% of patients were men, so this data may not apply to women.
In patients at high risk ( 1-2 % per year TIMI risk score) or with established coronary disease, there is no questions that they are beneficial. They reduce inflammation besides lowering cholesterol, and stabilize plaque both in cardiovascular system and other vascular beds including the brain and kidneys. THey reduce the risk for strokes in patients with CAD and with TIAs/ strokes, and they may be protective against development of ALzheimer's or other dementias.
They are not perfect however. The original statin ( Lovastatin now called Mevacor) when given to animals in high doses caused enlargement of the gut cells' Endoplasmic reticulum and this was mistaken for bowel lymphoma. No other cancers have been linked. The statins can also cause a myositis in some patients, manifested by muscle inflammation and breakdown. This decreases the ability of muscle to function appropriately and is probably responsible for your decrease in performance. In my practice, I usually check a CK or myoglobin level if symptoms such as these occur, and if only midly elevated I start the patient on Coenzyme Q-10 ( Uiquinone). This is a vitamin which has been shown to be present at low levels in patients on statins.

I am taking 60mg of CoQ10 per day.
should I take more?
Will it help restore performance?
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Old 07-28-09, 09:19 PM
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Originally Posted by 80vette View Post
The doc put me on statins to lower my chloresterol.
That was about 3 weeks ago.

My ride performance has gone down hill.

I am easily winded.
Speed that I could hold at 75% MHR now takes 85% or more.
If I ride at 75% MHR speed is down 1.5 to 2 mph.

WTF?
Thoughts
Your brakes are dragging.





Srsly - go ask a doctor, not a bike forum.
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Old 07-28-09, 09:35 PM
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Unless you're a pro cyclist and this will affect your performance and job, why the heck do you care?? The docs don't prescribe unless you need the stuff. Get real, dude. Take the medicince, live longer, and don't worry about something as trivial as MHR speed reduced by 1.5mph. Honestly, this is one of the most childish OP's I have read in a long time. Grow up - if you're on these meds then you're grown up age wise but mentally your still very much a child and lack the maturity to prioritize.


Originally Posted by 80vette View Post
The doc put me on statins to lower my chloresterol.
That was about 3 weeks ago.

My ride performance has gone down hill.

I am easily winded.
Speed that I could hold at 75% MHR now takes 85% or more.
If I ride at 75% MHR speed is down 1.5 to 2 mph.

WTF?
Thoughts
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Old 07-29-09, 12:16 AM
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you'd be pretty annoyed, too, if you suddenly lost 2 mph.
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Old 07-29-09, 07:12 AM
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Originally Posted by ironhorse3 View Post
I think your reduced performance could be medication related, but may not be. Discuss this with your doctor. Also, to be an informed statin user, you could determine your 10 year NCEP (National Cholesterol Education Program) risk for a stroke or heart attack using a validated method available on the internet. Give this value to your healthcare provider. Look on Google and use "10 year NCEP risk calculator" as the search phrase. You have to enter your age, sex, systolic blood pressure, smoking status (hopefully nonsmoker!), total cholesterol, and HDL level (prior to starting the statin). This method is not valid for diabetics, however (as they are at relatively higher risk and are usually in need of taking the Statin).

If you are young, and do not smoke or have high blood pressure, and actually have a decent HDL, your doctor may be persuaded to let you go off the Statin.
It's always best to follow your doctor's instructions, but sometimes doctors may not realize that you actually are not at high risk. If they are reasonable they will not resent you taking an interest and discussing this information with them.

Good luck.
I have not at all found this to be the case. YMMV.
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Old 07-29-09, 07:16 AM
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Originally Posted by markwebb View Post
Unless you're a pro cyclist and this will affect your performance and job, why the heck do you care?? The docs don't prescribe unless you need the stuff. Get real, dude. Take the medicince, live longer, and don't worry about something as trivial as MHR speed reduced by 1.5mph. Honestly, this is one of the most childish OP's I have read in a long time. Grow up - if you're on these meds then you're grown up age wise but mentally your still very much a child and lack the maturity to prioritize.
incorrect
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Old 07-29-09, 07:21 AM
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Maybe it's the reason they call it a practice? Sooner or later they will get it right? I always check pricing, I also check advice from Doc's..... Second opinions never a bad idea.
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Old 07-29-09, 07:36 AM
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Originally Posted by kyakdiver View Post
Maybe it's the reason they call it a practice? Sooner or later they will get it right? I always check pricing, I also check advice from Doc's..... Second opinions never a bad idea.
This is a valid point, but second opinion from internet...not so much.
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Old 07-29-09, 08:05 AM
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Muscle weakness is a normal side effect of these drugs. Tell you doc and try another drug. This is usually one of the earlier choices due to cost. As far as a the poster claiming medical scam don't accept that foolishness. There is a strong correlation between high cholesterol and cardiac disease.

You want to avoid that unfortunate irreversable side effect from high cholesterol........death.
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Old 07-29-09, 08:11 AM
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Originally Posted by Beaker View Post
This is a valid point, but second opinion from internet...not so much.
This place was not the second opinion I was thinking of...
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Old 07-29-09, 08:59 AM
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Originally Posted by markwebb View Post
Unless you're a pro cyclist and this will affect your performance and job, why the heck do you care?? The docs don't prescribe unless you need the stuff. Get real, dude. Take the medicince, live longer, and don't worry about something as trivial as MHR speed reduced by 1.5mph. Honestly, this is one of the most childish OP's I have read in a long time. Grow up - if you're on these meds then you're grown up age wise but mentally your still very much a child and lack the maturity to prioritize.
Thank you so much for your well thought out, mature insight.
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Old 07-29-09, 09:25 AM
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non doctors playing doctor are funny
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Old 07-29-09, 09:27 AM
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I'm on the same scrip, and I have to say I've had no adverse affects. Cholesterol has been noticably reduced since I started taking it in December, and to be honest, I've found myself working harder on the bike. Average speed is up 2mph since March, and I feel great. Obviously, different things affect different people in different ways, but I don't know that I'd jump to the conclusion that it's the statin that's the cause.

But yeah, talk to your doctor, I'd say.
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Old 07-29-09, 09:45 AM
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For what it's worth I'm taking a 20mg simvastatin. I can't say I've noticed any effects on performance.
Although I recently as of Feb really started working out again. I started with push up and crunches working my way up to 50+ consecutive push ups and 100+crunches. Started running on the treadmill at work, and have been cycling. I've only experienced a decrease in my resting heart rate. Increased performance and last night I ran my best mile time of under 12mins, getting close to my goal of 8mins.

If you have just started taking it maybe you need to give yourself an adjustment period.
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Old 07-29-09, 09:49 AM
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Old 07-29-09, 10:00 AM
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Niaspan?
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Old 07-29-09, 10:24 AM
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My wife worked in a cardiac rehab facility for about 18 months, doing physical therapy / training with the high risk clients. Most of the patients were on statins, or started taking statins while they were there. She said the strength decrease was so bad for those on statins, especially on the older clients (50+), that she would call the patients doctors and see if it was absolutely necessary for them to be taking them. It really scared the hell out of her, because patients would all of a sudden stop making progress, and then lose strength out of nowhere.

All I know is that can't be good for you.
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Old 07-29-09, 10:34 AM
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Originally Posted by save10 View Post
non doctors playing doctor are funny
Even worse are doctors playing doctor.

They prescribe statins for any old reason and then we have all these fake or poorly done studies that show "all the benefits" of statins that doctors almost never read, and certainly never thoroughly read or research. They all just serve to sell more drugs for the drug company's.

https://www.proteinpower.com/drmike/s...nd-drug-money/
Here is a little bit on just how much money is made from this stuff.

And here is a good critical look at one of the more recent "groundbreaking" statin studies.
https://www.proteinpower.com/drmike/c...-disease/1853/

Last edited by dsellinger; 07-29-09 at 10:39 AM. Reason: Add link, yes I'm a Dr Eades shill. :p
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