I'm in the same boat as you- I tour with a lot of gear and I weigh 200 pounds. Heads up. Gear breaks faster for us.

I have a XO-1 that I toured on, but not for weeks on end. The longest with it is a week long local tour. Have a Panasonic Pro Touring and Miyata 1000, but my tourer of choice is a Miyata 618. It's strong and comfortable and I've had no problems with it. If you're worried about break downs, then you might want to consider converting a mountain bike. The 80s mb are great rigs, super strong and great geometry for touring, and many are lugged which is a nice esthetic touch.
good luck.