Mostly no, but I did once threw my butt off my seat by locking the front brake only.

What happen was that I just got home on my road bike which had rim brakes. A little while later, I needed to get something from the other side of town and took the mountain bike which had disc brakes and front suspension only which was in the locked position. I chose that bike since my route involve some heavy motorist traffic and I rather ride the sidewalk in that short stretch where it was heavy. I got so used to braking with the rim brakes on my road bike that I forgot how much smoother my disc brake react. I was using my right hand pushing my shoulder bag behind me when I reached the intersection. I was still in motion when a car decided to turn right and cut into the corner and onto the sidewalk. I slam on the front brake hard. Threw the back end of the bike in the air more than a foot making my butt slip out of my seat. All this because I was so used to my rim brakes from my earlier ride and being careless.