I alternate between a Surly CrossCheck with 50/39/30 with 12-27 cassette, and a Cannondale Synapse 50/34 also with a 12-27, and I climb better on the Cannondale. Combination of weight (mostly I'd guess), efficiency, and frame design seems to tip the scale. If you've got a 12-27 cassette on your Sequoia and only rarely use the 27, you'll be fine. If your relying on the 27 continually, you may be better with the triple.