Ride the route a couple of times to see how difficult it is and how long it takes. You might come up with a better route along the way.

The first time you do the commute leave a bit early because the traffic will be different than when you did your trial runs.

It'll get easier the more you do it, so don't be discouraged the first time you do it. It nearly killed me when I did a trial run of my commute for the first time because I picked a really bad route. That's why it's a good idea to try it out before the real thing happens.