I've been using the "regular" (not Supreme) Schwalbe Marathons 622 X 47mm as well as 622 x 37mm in their previous designations HS 308 and HS270 for the past 12+ years for daily commuting and in over 55,000 miles have not had any flat tires that required a road side fix; only a few slow leakers that could be patched at either work or at home. They ride great and also last for years.