I have had perfectly smooth hubs but they are rare.
Your hub is surely way too tight, though, because a correctly tensioned quick release actually has the power to compress the axle a bit, so the bearings get a lot tighter when the wheel is clamped in your bike. So, the bearings have to be adjusted with a bit of slack which goes away when the quick release clamps onto the axle.
There are little irregularities on even very good bearings sometimes and you can feel a lumpiness.
However, when the qr is removed the axle should feel loose. You can even feel it wobble just a little when there are no rubber seals to hold it in place, like on an older bike.
Get that thing serviced, or get some cone wrenches and do it yourself.