and i went the other way with my fixie wheelset. 32 3x front and back, hooked to aerohead rims and phil hubs. they're bulletproof and i doubt that they'll come out of true often.
on my roadie, i have 24 radial up front and 28 3x in the back (velomax circuits). i wind up re-truing them every 8-12 months or so.
so, i guess it's all about how well you build your wheels, and how you use them. my fixie is supposed to be an urban assault vehicle, so i wanted stronger wheels. my roadie is made for long distances and controlled training rides, so....
have at it!