I run a 12-25 or 11-25 on all my bikes, the one exception is my Zipp 404 tubular race wheels, those have an 11-23. If I'm racing or on a fast group ride like Nyack, even when climbing there really isn't a call for that 25; if you have to bail to the 25 you're going to get shelled. For other rides the hills around here (particularly Mt. Doom) are too ball busting for your granny gear to be a 23.

I do like the 11-25 set up that they have now on the 10 speed 7900 and Ultegra 6700 cassettes. Not much need for that 11 I suppose, but it does give you some more oomph hammering on fast descents.