Look ahead to avoid big holes, and generally ride with supple body posture. As you ride more, you will get better at spotting road imperfections and either avoiding them or relaxing over them. If really rough, unavoidable pavement, you generally balance evenly on your pedals and handlebars, with butt off the saddle. Relax, relax, relax. Helps if you've ridden a mtn bike. Have a good time riding.