It should, mostly it comes down to the size of the needle and thread that it will take, and how many layers of fabric. Some types of seems really get thick, just look at a pair of Levy jeans. I really don't know a huge lot about sewing yet though. I just got through the fabric and some thread stuff!
This is the strongest most waterresistant seam I know of, I don't recall it's name but it's used on jeans.
the top is the first step, the bottom is second, light green is first step stitching, dark green is second step stitching, red and blue are fabric. It requires sewing through four layers of fabric.