I've met several solo women on the road and none of them seemed to have experienced anything untoward. I met one on the Ice Fields who came solo from Denali! And they were all very friendly with me from the get go. My guess is that if you're the kind of person who is rarely "creeped out", then you likely won't be creeped out on the road either. But Valgrl's advice is sound. In fact, I follow it too!